Epidrugs as Promising Tools to Eliminate <i>Plasmodium falciparum</i> Artemisinin-Resistant and Quiescent Parasites

• Main Authors: Thibaud Reyser (Author), Lucie Paloque (Author), Michel Nguyen (Author), Jean-Michel Augereau (Author), Matthew John Fuchter (Author), Marie Lopez (Author), Paola B. Arimondo (Author), Storm Hassell-Hart (Author), John Spencer (Author), Luisa Di Stefano (Author), Françoise Benoit-Vical (Author)
• Format: Book
• Published: MDPI AG, 2023-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The use of artemisinin and its derivatives has helped reduce the burden of malaria caused by <i>Plasmodium falciparum.</i> However, artemisinin-resistant parasites are able, in the presence of artemisinins, to stop their cell cycles. This quiescent state can alter the activity of artemis...