Low MiR-187 Expression Promotes Resistance to Chemoradiation Therapy In Vitro and Correlates with Treatment Failure in Patients with Esophageal Adenocarcinoma

• Main Authors: Niamh Lynam-Lennon (Author), Becky A S Bibby (Author), Ann Marie Mongan (Author), Laure Marignol (Author), Christian N Paxton (Author), Katherine Geiersbach (Author), Mary P Bronner (Author), Jacintha O'Sullivan (Author), John V Reynolds (Author), Stephen G Maher (Author)
• Format: Book
• Published: BMC, 2016-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Esophageal adenocarcinoma (EAC) has a poor prognosis and is increasing in incidence in many Western populations. Neoadjuvant chemoradiation therapy (CRT) followed by surgery is increasingly the standard of care for locally advanced EAC; however, resistance to treatment is a significant clin...