Low MiR-187 Expression Promotes Resistance to Chemoradiation Therapy In Vitro and Correlates with Treatment Failure in Patients with Esophageal Adenocarcinoma

• Главные авторы: Niamh Lynam-Lennon (Автор), Becky A S Bibby (Автор), Ann Marie Mongan (Автор), Laure Marignol (Автор), Christian N Paxton (Автор), Katherine Geiersbach (Автор), Mary P Bronner (Автор), Jacintha O'Sullivan (Автор), John V Reynolds (Автор), Stephen G Maher (Автор)
• Формат: ‌
• Опубликовано: BMC, 2016-05-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

Abstract Esophageal adenocarcinoma (EAC) has a poor prognosis and is increasing in incidence in many Western populations. Neoadjuvant chemoradiation therapy (CRT) followed by surgery is increasingly the standard of care for locally advanced EAC; however, resistance to treatment is a significant clin...