Tritiated Water Induces Toxicity in Human Umbilical Vein Vascular Endothelial Cells via IL8

• Main Authors: Hong-Bin Yan (Author), Yi-Tong Liu (Author), Zhen-Yan Li (Author), Zhuo-Jun Wu (Author), Meng Zhang (Author), Pei-Jun Xue (Author), Yu-Long Liu (Author), Kong-Zhao Wang (Author), Yong-Ming He (Author), Yu Tu (Author), Feng-Mei Cui (Author), Qiu Chen (Author)
• Format: Book
• Published: SAGE Publishing, 2020-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We aimed to determine the toxic effects of tritiated water (HTO) on 12 generations (T1-T12) of human umbilical vein vascular endothelial cells (HUVECs) and elucidate the underlying mechanisms. We evaluated cellular senescence, interleukin (IL) 8 concentrations, and angiogenesis using β-galactosidase...