Pravastatin Induces Rat Aortic Endothelial Cell Proliferation and Migration via Activation of PI3K/Akt/mTOR/p70 S6 Kinase Signaling

• Главные авторы: Takafumi Nakao (Автор), Masayuki Shiota (Автор), Yasuyoshi Tatemoto (Автор), Yasukatsu Izumi (Автор), Hiroshi Iwao (Автор)
• Формат: ‌
• Опубликовано: Elsevier, 2007-01-01T00:00:00Z.
• Предметы: article
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The HMG-CoA reductase inhibitors (statins) have been shown to exert several vascular protective effects that are not related to changes in cholesterol profile, and these effects of statins are partly caused by the activation of angiogenesis. Endothelial cell (EC) proliferation and migration are cruc...