Different spectrophotometric and TLC-densitometric methods for determination of pyrazinamide in presence of its impurity

• Main Authors: Neven Magdy Habib (Author), Nourudin Wagih Ali (Author), Nada Sayed Abdelwhab (Author), Maha Mohamed Abdelrahman (Author)
• Format: Book
• Published: Faculty of Pharmacy, Cairo University, 2017-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In this search, three selective spectrophotometric and TLC-densitometric methods have been developed and validated for quantitative determination of Pyrazinamide (PYN) and its impurity, Pyrazine-2-carboxylic acid (PYA). The proposed methods are third derivative spectrophotometric (Method I), first d...