The transcription factor Nurr1 is upregulated in amyotrophic lateral sclerosis patients and SOD1-G93A mice

• Main Authors: Valeria Valsecchi (Author), Marina Boido (Author), Francesca Montarolo (Author), Michela Guglielmotto (Author), Simona Perga (Author), Serena Martire (Author), Santina Cutrupi (Author), Andrea Iannello (Author), Nadia Gionchiglia (Author), Elena Signorino (Author), Andrea Calvo (Author), Giuseppe Fuda (Author), Adriano Chiò (Author), Antonio Bertolotto (Author), Alessandro Vercelli (Author)
• Format: Book
• Published: The Company of Biologists, 2020-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that affects both lower and upper motor neurons (MNs) in the central nervous system. ALS etiology is highly multifactorial and multifarious, and an effective treatment is still lacking. Neuroinflammation is a hallmark of ALS and coul...