Molecular docking and synthesis of N-alkyl-isatin-3-imino aromatic amine derivatives and their antileishmanial and cytotoxic activities

• Auteurs principaux: Farshid Hassanzadeh (Auteur), Seyed Hossein Hejazi (Auteur), Elham Jafari (Auteur), Atefeh Mohammadi fard (Auteur), Hojjat Sadeghi-aliabadi (Auteur)
• Format: Livre
• Publié: Wolters Kluwer Medknow Publications, 2024-01-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Background and purpose: Isatin derivatives have excited attention due to their biological attractions, especially, anticancer properties. Isatin analogs such as semaxanib and sunitinib were exposed to tyrosine kinase inhibitory properties. N-substituted isatins were reported to show cytotoxic activi...