Targeted Delivery of 5-Fluorouracil and Sonidegib via Surface-Modified ZIF-8 MOFs for Effective Basal Cell Carcinoma Therapy

• Main Authors: Bharath Singh Padya (Author), Gasper Fernandes (Author), Sumukha Hegde (Author), Sanjay Kulkarni (Author), Abhijeet Pandey (Author), Praful Balavant Deshpande (Author), Sheikh F. Ahmad (Author), Dinesh Upadhya (Author), Srinivas Mutalik (Author)
• Formato: Livro
• Publicado em: MDPI AG, 2023-11-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

The therapeutic effectiveness of the most widely used anticancer drug 5-fluorouracil (5-FU) is constrained by its high metabolism, short half-life, and rapid drug resistance after chemotherapy. Although various nanodrug delivery systems have been reported for skin cancer therapy, their retention, pe...