Synthesis, anti-bacterial and anti-protozoal activities of amidinobenzimidazole derivatives and their interactions with DNA and RNA

• Main Authors: Andrea Bistrović (Author), Luka Krstulović (Author), Ivana Stolić (Author), Domagoj Drenjančević (Author), Jasminka Talapko (Author), Martin C. Taylor (Author), John M. Kelly (Author), Miroslav Bajić (Author), Silvana Raić-Malić (Author)
• Format: Book
• Published: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Amidinobenzimidazole derivatives connected to 1-aryl-substituted 1,2,3-triazole through phenoxymethylene linkers 7a-7e, 8a-8e, and 9a-9e were designed and synthesised with the aim of evaluating their anti-bacterial and anti-trypanosomal activities and DNA/RNA binding affinity. Results from anti-bact...