Association of tet methylcytosine dioxygenase 2 and 5-hydroxymethylcytosine in endometrioid adenocarcinoma and its clinical significance

• Autori principali: Lei Kuang (Autore), Jingbo Zhang (Autore), Yanyu Li (Autore), Qing Wang (Autore), Jianwei Liu (Autore), Bei Zhang (Autore)
• Natura: Libro
• Pubblicazione: BMC, 2024-03-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Abstract Background Aberrant DNA methylation is a vital molecular alteration commonly detected in type I endometrial cancers (EC), and tet methylcytosine dioxygenase 2 (TET2) and 5-hydroxymethylcytosine (5hmC) play significant roles in DNA demethylation. However, little is known about the function a...