Association of tet methylcytosine dioxygenase 2 and 5-hydroxymethylcytosine in endometrioid adenocarcinoma and its clinical significance

• Main Authors: Lei Kuang (Author), Jingbo Zhang (Author), Yanyu Li (Author), Qing Wang (Author), Jianwei Liu (Author), Bei Zhang (Author)
• Formato: Livro
• Publicado em: BMC, 2024-03-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Abstract Background Aberrant DNA methylation is a vital molecular alteration commonly detected in type I endometrial cancers (EC), and tet methylcytosine dioxygenase 2 (TET2) and 5-hydroxymethylcytosine (5hmC) play significant roles in DNA demethylation. However, little is known about the function a...