Penfluroidol Attenuates the Imbalance of the Inflammatory Response by Repressing the Activation of the NLRP3 Inflammasome and Reduces Oxidative Stress via the Nrf2/HO-1 Signaling Pathway in LPS-Induced Macrophages

• Váldodahkkit: Qiulin Li (Dahkki), Lidong Wu (Dahkki), Bin Cheng (Dahkki), Shaoyu Tao (Dahkki), Wei Wang (Dahkki), Zhiqiang Luo (Dahkki), Jun Fan (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Hindawi Limited, 2023-01-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Objectives. Excessive inflammatory responses and reactive oxygen species (ROS) formation play pivotal roles in the pathogenesis of sepsis. Penfluroidol (PF), an oral long-acting antipsychotic drug, has been suggested to possess diverse biological properties, including antischizophrenia, antitumour e...