MiRNA/mRNA network topology in hepatitis virus B-related liver cirrhosis reveals miR-20a-5p/340-5p as hubs initiating fibrosis

MiRNA/mRNA network topology in hepatitis virus B-related liver cirrhosis reveals miR-20a-5p/340-5p as hubs initiating fibrosis

Abstract Background The pathophysiology of hepatitis B-related liver cirrhosis (HBV-LC) remains unclear. This study aimed to explore the disease mechanisms using topological analysis of the miRNA/mRNA network. Methods Paired miRNA/mRNA sequencing was performed with thirty-three peripheral blood mono...

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Main Authors: Heng Yao (Author), Peng Li (Author), Jiaojiao Xin (Author), Xi Liang (Author), Jing Jiang (Author), Dongyan Shi (Author), Jiang Li (Author), Hozeifa Mohamed Hassan (Author), Xin Chen (Author), Jun Li (Author)
Format: Book
Published: BMC, 2022-11-01T00:00:00Z.
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