Novel DYRK1A Inhibitor Rescues Learning and Memory Deficits in a Mouse Model of Down Syndrome

• Main Authors: Wenche Stensen (Author), Ulli Rothweiler (Author), Richard Alan Engh (Author), Melissa R. Stasko (Author), Ilya Bederman (Author), Alberto C. S. Costa (Author), Anders Fugelli (Author), John S. Mjøen Svendsen (Author)
• Format: Book
• Published: MDPI AG, 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Down syndrome (DS) is a complex genetic disorder associated with substantial physical, cognitive, and behavioral challenges. Due to better treatment options for the physical co-morbidities of DS, the life expectancy of individuals with DS is beginning to approach that of the general population. Howe...