Structural Elucidation of Antibiotic TKR2999, an Antifungal Lipodepsipeptide Isolated from the Fungus <i>Foliophoma fallens</i>

• Main Authors: Gloria Crespo (Author), Ignacio Pérez-Victoria (Author), Francisco Javier Ortiz-López (Author), Víctor González-Menéndez (Author), Mercedes de la Cruz (Author), Bastien Cautain (Author), Pilar Sánchez (Author), Francisca Vicente (Author), Olga Genilloud (Author), Fernando Reyes (Author)
• Format: Book
• Published: MDPI AG, 2020-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

An antifungal lipodepsipeptide was obtained from cultures of the fungus <i>Foliophoma fallens</i> CF-236885. Its structure, elucidated by HRMS and NMR spectroscopy, contained Gly, Thr, Asn, β-Ala, Orn, Ala, two Ser residues, and 3-hydroxy-4-methylhexadecanoic acid. The absolute configura...