β-Hydroxyisovalerylshikonin regulates macrophage polarization via the AMPK/Nrf2 pathway and ameliorates sepsis in mice

Context The potential anti-inflammatory bioactivities of β-hydroxyisovalerylshikonin (β-HIVS) remain largely unknown.Objective This study investigated the anti-inflammatory effects and underlying mechanisms of β-HIVS.Materials and methods RAW 264.7 cells stimulated with LPS (100 ng/mL) for 24 h were...

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Main Authors: Tao Pan (Author), Yabin Chang (Author), Min He (Author), Zehui He (Author), Jun Jiang (Author), Xinling Ren (Author), Fang Zhang (Author)
Format: Book
Published: Taylor & Francis Group, 2022-12-01T00:00:00Z.
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