Novel Survivin Inhibitor YM155 elicits Cytotoxicity in Glioblastoma Cell Lines with Normal or Deficiency DNA-Dependent Protein Kinase Activity

• Үндсэн зохиолчид: Pei Chun Lai (Зохиогч), Shu Huey Chen (Зохиогч), Shang Hsien Yang (Зохиогч), Chuan Chu Cheng (Зохиогч), Ted H. Chiu (Зохиогч), Yen Ta Huang (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Elsevier, 2012-06-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Pediatric glioblastoma is a malignant disease with an extremely poor clinical outcome. Patients usually suffer from resistance to radiation therapy, so targeted drug treatment may be a new possibility for glioblastoma therapy. Survivin is also overexpressed in glioblastoma. YM155, a novel small-mole...