Sensitive and reliable detection of Kit point mutation Asp 816 to Val in pathological material

<p>Abstract</p> <p>Background</p> <p>Human mastocytosis is a heterogenous disorder which is linked to a gain-of-function mutation in the kinase domain of the receptor tyrosine kinase Kit. This D816V mutation leads to constitutive activation and phosphorylation of Kit wi...

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Main Authors: Feller Alfred C (Author), Didlaukat Sabine (Author), Kähler Christian (Author), Merz Hartmut (Author)
Format: Book
Published: BMC, 2007-09-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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