Simvastatin and Benznidazole-Mediated Prevention of Trypanosoma cruzi-Induced Endothelial Activation: Role of 15-epi-lipoxin A4 in the Action of Simvastatin.

• Main Authors: Carolina Campos-Estrada (Author), Ana Liempi (Author), Fabiola González-Herrera (Author), Michel Lapier (Author), Ulrike Kemmerling (Author), Barbara Pesce (Author), Jorge Ferreira (Author), Rodrigo López-Muñoz (Author), Juan D Maya (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2015-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Trypanosoma cruzi is the causal agent of Chagas Disease that is endemic in Latin American, afflicting more than ten million people approximately. This disease has two phases, acute and chronic. The acute phase is often asymptomatic, but with time it progresses to the chronic phase, affecting the hea...