Maternal-Neonatal Raltegravir Population Pharmacokinetics Modeling: Implications for Initial Neonatal Dosing

• मुख्य लेखकों: Jos Lommerse (लेखक), Diana Clarke (लेखक), Thomas Kerbusch (लेखक), Henri Merdjan (लेखक), Han Witjes (लेखक), Hedy Teppler (लेखक), Mark Mirochnick (लेखक), Edward P. Acosta (लेखक), Larissa Wenning (लेखक), Sharon Nachman (लेखक), Anne Chain (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Wiley, 2019-09-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Raltegravir readily crosses the placenta to the fetus with maternal use during pregnancy. After birth, neonatal raltegravir elimination is highly variable and often extremely prolonged, with some neonates demonstrating rising profiles after birth despite removal from the source of extrinsic raltegra...