Pioglitazone Synthetic Analogue Ameliorates Streptozotocin-Induced Diabetes Mellitus through Modulation of ACE 2/Angiotensin 1-7 via PI3K/AKT/mTOR Signaling Pathway

• Main Authors: Yasmin M. Ahmed (Author), Mohamed A. Abdelgawad (Author), Khaled Shalaby (Author), Mohammed M. Ghoneim (Author), Asmaa M. AboulMagd (Author), Nada S. Abdelwahab (Author), Hossam M. Hassan (Author), Asmaa M. Othman (Author)
• Format: Book
• Published: MDPI AG, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The renin angiotensin aldosterone system has a localized key regulatory action, especially in liver and body circulation. Furthermore, it accomplishes a significant role in the downregulation of the PI3K/AKT/mTOR signaling pathway that is involved in type II diabetes mellitus pathogenesis. The curre...