Mycobactin analogue interacting with siderophore efflux-pump protein: insights from molecular dynamics simulations and whole-cell assays

• Päätekijät: Mousumi Shyam (Tekijä), Abhishek Thakur (Tekijä), Caroline Velez (Tekijä), Chris Daniel (Tekijä), Orlando Acevedo (Tekijä), Sanjib Bhakta (Tekijä), Venkatesan Jayaprakash (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Frontiers Media S.A., 2024-05-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

IntroductionIn response to continued public health emergency of antimicrobial resistance (AMR), a significant key strategy is the discovery of novel mycobacterial efflux-pump inhibitors (EPIs) as potential adjuvants in combination drug therapy. Interest in identifying new chemotypes which could pote...