DNA methylation abnormalities of imprinted genes in congenital heart disease: a pilot study

• Main Authors: Shaoyan Chang (Author), Yubo Wang (Author), Yu Xin (Author), Shuangxing Wang (Author), Yi Luo (Author), Li Wang (Author), Hui Zhang (Author), Jia Li (Author)
• Format: Book
• Published: BMC, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Congenital heart disease (CHD) is resulted from the interaction of genetic aberration and environmental factors. Imprinted genes, which are regulated by epigenetic modifications, are essential for the normal embryonic development. However, the role of imprinted genes in the etiol...