Royleanone Derivatives From Plectranthus spp. as a Novel Class of P-Glycoprotein Inhibitors

• Main Authors: Catarina Garcia (Author), Vera M. S. Isca (Author), Filipe Pereira (Author), Carlos M. Monteiro (Author), Epole Ntungwe (Author), Francisco Sousa (Author), Jelena Dinic (Author), Suvi Holmstedt (Author), Amílcar Roberto (Author), Ana Díaz-Lanza (Author), Catarina P. Reis (Author), Milica Pesic (Author), Nuno R. Candeias (Author), Ricardo J. Ferreira (Author), Noélia Duarte (Author), Carlos A. M. Afonso (Author), Patrícia Rijo (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cancer is among the leading causes of death worldwide. One of the most challenging obstacles in cancer treatment is multidrug resistance (MDR). Overexpression of P-glycoprotein (P-gp) is associated with MDR. The growing incidence of cancer and the development of MDR drive the search for novel and mo...