Influence of Oleic Acid on the Rheology and in Vitro Release of Lumiracoxib from Poloxamer Gels
Abstract PURPOSE: Transdermal delivery of anti-inflammatory lumiracoxib (LM) could be an interesting strategy to avoid the side effects associated with systemic delivery, but it is ineffective due to the drug poor skin penetration. We have investigated the effects of oleic acid (OA), a lipid penetra...
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Format: | Book |
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Frontiers Media S.A.,
2010-08-01T00:00:00Z.
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A1234.567 |
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Copy 1 | Available |