Synthesis of Novel, Dual-Targeting ⁶⁸Ga-NODAGA-LacN-E[c(RGDfK)]₂ Glycopeptide as a PET Imaging Agent for Cancer Diagnosis

• Main Authors: Barbara Gyuricza (Author), Judit P. Szabó (Author), Viktória Arató (Author), Dániel Szücs (Author), Adrienn Vágner (Author), Dezső Szikra (Author), Anikó Fekete (Author)
• Format: Book
• Published: MDPI AG, 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Radiolabeled peptides possessing an Arg-Gly-Asp (RGD) motif are widely used radiopharmaceuticals for PET imaging of tumor angiogenesis due to their high affinity and selectivity to α_vβ₃ integrin. This receptor is overexpressed in tumor and tumor endothel...