Synthesis of Novel, Dual-Targeting ⁶⁸Ga-NODAGA-LacN-E[c(RGDfK)]₂ Glycopeptide as a PET Imaging Agent for Cancer Diagnosis

• Prif Awduron: Barbara Gyuricza (Awdur), Judit P. Szabó (Awdur), Viktória Arató (Awdur), Dániel Szücs (Awdur), Adrienn Vágner (Awdur), Dezső Szikra (Awdur), Anikó Fekete (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: MDPI AG, 2021-05-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Radiolabeled peptides possessing an Arg-Gly-Asp (RGD) motif are widely used radiopharmaceuticals for PET imaging of tumor angiogenesis due to their high affinity and selectivity to α_vβ₃ integrin. This receptor is overexpressed in tumor and tumor endothel...