Mitochondrial proteomic profile of complex IV deficiency fibroblasts: rearrangement of oxidative phosphorylation complex/supercomplex and other metabolic pathways

• Main Authors: Karina Salvador-Severo (Author), Leopoldo Gómez-Caudillo (Author), Héctor Quezada (Author), José de Jesús García-Trejo (Author), Alan Cárdenas-Conejo (Author), Martha Elisa Vázquez-Memije (Author), Fernando Minauro-Sanmiguel (Author)
• Format: Book
• Published: Permanyer, 2017-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Mitochondriopathies are multisystem diseases affecting the oxidative phosphorylation (OXPHOS) system. Skin fibroblasts are a good model for the study of these diseases. Fibroblasts with a complex IV mitochondriopathy were used to determine the molecular mechanism and the main affected fu...