Mitochondrial proteomic profile of complex IV deficiency fibroblasts: rearrangement of oxidative phosphorylation complex/supercomplex and other metabolic pathways

• Hoofdauteurs: Karina Salvador-Severo (Auteur), Leopoldo Gómez-Caudillo (Auteur), Héctor Quezada (Auteur), José de Jesús García-Trejo (Auteur), Alan Cárdenas-Conejo (Auteur), Martha Elisa Vázquez-Memije (Auteur), Fernando Minauro-Sanmiguel (Auteur)
• Formaat: Boek
• Gepubliceerd in: Permanyer, 2017-05-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Background: Mitochondriopathies are multisystem diseases affecting the oxidative phosphorylation (OXPHOS) system. Skin fibroblasts are a good model for the study of these diseases. Fibroblasts with a complex IV mitochondriopathy were used to determine the molecular mechanism and the main affected fu...