Mechanical Hypersensitivity and Alterations in Cutaneous Nerve Fibers in a Mouse Model of Skin Cancer Pain

• Main Authors: Hong-Wei Zhang (Author), Yuko Iida (Author), Tsugunobu Andoh (Author), Hiroshi Nojima (Author), Jun Murata (Author), Ikuo Saiki (Author), Yasushi Kuraishi (Author)
• Format: Book
• Published: Elsevier, 2003-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Melanoma inoculation induced marked mechanical allodynia and hyperalgesia in the periphery of the melanoma mass in mice from about day 10 post-inoculation. In the middle of the tumor, there were slight hyperalgesia and response disappearance in the early and late phases, respectively. PGP9.5-like im...