The effect of lengths of branched-chain fatty alcohols on the efficacy and safety of docetaxel-prodrug nanoassemblies

• Main Authors: Shuo Wang (Author), Tian Liu (Author), Yuetong Huang (Author), Chaoying Du (Author), Danping Wang (Author), Xiyan Wang (Author), Qingzhi Lv (Author), Zhonggui He (Author), Yinglei Zhai (Author), Bingjun Sun (Author), Jin Sun (Author)
• Format: Book
• Published: Elsevier, 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The self-assembly prodrugs are usually consisted of drug modules, activation modules, and assembly modules. Keeping the balance between efficacy and safety by selecting suitable modules remains a challenge for developing prodrug nanoassemblies. This study designed four docetaxel (DTX) prodrugs using...