Sirt3 regulated apoptosis and aerobic glycolysis during renal interstitial fibrosis

• Main Authors: Yong-hong Jian (Author), Yi-fei Yang (Author), Xue-yan Yang (Author), Ling-li Cheng (Author), Yu-han Wan (Author), Qian Guan (Author), Ding-ping Yang (Author)
• Format: Book
• Published: Editorial Department of Journal of Clinical Nephrology, 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective To observe the expression of silent information regulator 3 （Sirt3）, detect the level of aerobic glycolysis in renal fibrosis model and explore the role of Sirt3 in renal interstitial fibrosis. Methods Wild-type and Sirt3 gene knockout mice were utilized for constructing a renal fibrosis m...