The therapeutic targets and signaling mechanisms of ondansetron in the treatment of critical illness in the ICU

• Главные авторы: Lili Tao (Автор), Zhenhui Zhang (Автор), Chuang Li (Автор), Minxuan Huang (Автор), Ping Chang (Автор)
• Формат: ‌
• Опубликовано: Frontiers Media S.A., 2024-08-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

BackgroundThere is accumulating evidence regarding the benefits of the 5-HT3 receptor antagonist ondansetron for the treatment of critical illness due to its potential anti-inflammatory effect. This study attempted to determine the potential targets and molecular mechanisms of ondansetron's act...