Human iPSC- and Primary-Retinal Pigment Epithelial Cells for Modeling Age-Related Macular Degeneration

• Main Authors: Cody R. Fisher (Author), Mara C. Ebeling (Author), Zhaohui Geng (Author), Rebecca J. Kapphahn (Author), Heidi Roehrich (Author), Sandra R. Montezuma (Author), James R. Dutton (Author), Deborah A. Ferrington (Author)
• Format: Book
• Published: MDPI AG, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Primary cultures of retinal pigment epithelium (RPE) from human adult donors (haRPE) and induced pluripotent stem cell derived-RPE (iPSC-RPE) are valuable model systems for gaining mechanistic insight and for testing potential therapies for age-related macular degeneration (AMD). This study evaluate...