Human iPSC- and Primary-Retinal Pigment Epithelial Cells for Modeling Age-Related Macular Degeneration

• Κύριοι συγγραφείς: Cody R. Fisher (Συγγραφέας), Mara C. Ebeling (Συγγραφέας), Zhaohui Geng (Συγγραφέας), Rebecca J. Kapphahn (Συγγραφέας), Heidi Roehrich (Συγγραφέας), Sandra R. Montezuma (Συγγραφέας), James R. Dutton (Συγγραφέας), Deborah A. Ferrington (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: MDPI AG, 2022-03-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Primary cultures of retinal pigment epithelium (RPE) from human adult donors (haRPE) and induced pluripotent stem cell derived-RPE (iPSC-RPE) are valuable model systems for gaining mechanistic insight and for testing potential therapies for age-related macular degeneration (AMD). This study evaluate...