Encapsulation of morin in lipid core/PLGA shell nanoparticles significantly enhances its anti-inflammatory activity and oral bioavailability

• Main Authors: Suhair Sunoqrot (Author), Malak Alkurdi (Author), Abdel Qader Al Bawab (Author), Alaa M. Hammad (Author), Rabab Tayyem (Author), Ali Abu Obeed (Author), Mohammed Abufara (Author)
• Format: Book
• Published: Elsevier, 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Morin (3,5,7,2',4'-pentahydroxyflavone; MR) is a bioactive plant polyphenol whose therapeutic efficacy is hindered by its poor biopharmaceutical properties. The purpose of this study was to develop a nanoparticle (NP) formulation to enhance the bioactivity and oral bioavailability of MR. T...