RHBDF1 deficiency suppresses melanoma glycolysis and enhances efficacy of immunotherapy by facilitating glucose-6-phosphate isomerase degradation via TRIM32

• Asıl Yazarlar: Lei Wang (Yazar), Yuan-Yuan Song (Yazar), Yan Wang (Yazar), Xiu-Xiu Liu (Yazar), Yi-Lun Yin (Yazar), Shan Gao (Yazar), Fan Zhang (Yazar), Lu-Yuan Li (Yazar), Zhi-Song Zhang (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Elsevier, 2023-12-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Melanoma is a dangerous form of skin cancer, making it important to investigate new mechanisms and approaches to enhance the effectiveness of treatment. Here, we establish a positive correlation between the human rhomboid family-1 (RHBDF1) protein and melanoma malignancy. We demonstrate that the mel...