Vindoline Inhibits RANKL-Induced Osteoclastogenesis and Prevents Ovariectomy-Induced Bone Loss in Mice

• Main Authors: Yunfei Zhan (Author), Jiamin Liang (Author), Kun Tian (Author), Zhigang Che (Author), Ziyi Wang (Author), Xue Yang (Author), Yuangang Su (Author), Xixi Lin (Author), Fangming Song (Author), Jinmin Zhao (Author), Jiake Xu (Author), Qian Liu (Author), Bo Zhou (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Osteolytic bone diseases, for example postmenopausal osteoporosis, arise from the imbalances between osteoclasts and osteoblasts in the bone remodeling process, whereby osteoclastic bone resorption greatly exceeds osteoblastic bone formation resulting in severe bone loss and deterioration in bone st...