Psoriatic skin inflammation induces a pre-diabetic phenotype via the endocrine actions of skin secretome

• Main Authors: Elizabeth A. Evans (Author), Sophie R. Sayers (Author), Xenia Kodji (Author), Yue Xia (Author), Mahum Shaikh (Author), Alizah Rizvi (Author), James Frame (Author), Susan D. Brain (Author), Michael P. Philpott (Author), Rosalind F. Hannen (Author), Paul W. Caton (Author)
• Format: Book
• Published: Elsevier, 2020-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Psoriasis is a chronic inflammatory skin disease that is thought to affect ∼2% of the global population. Psoriasis has been associated with ∼30% increased risk of developing type 2 diabetes (T2D), with numerous studies reporting that psoriasis is an independent risk-factor for T2D, separa...