Rhein Suppresses Lung Inflammatory Injury Induced by Human Respiratory Syncytial Virus Through Inhibiting NLRP3 Inflammasome Activation via NF-κB Pathway in Mice

• Main Authors: Cunsi Shen (Author), Zhengguang Zhang (Author), Tong Xie (Author), Jianjian Ji (Author), Jianya Xu (Author), Lili Lin (Author), Jing Yan (Author), An Kang (Author), Qigang Dai (Author), Yingmei Dong (Author), Jinjun Shan (Author), Shouchuan Wang (Author), Xia Zhao (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Rhein is one of active anthraquinone components in traditional Chinese herbal medicine Rheum palmatum L., possessing anti-inflammatory, antioxidant, antitumor, antiviral, and hepatoprotective activities. Human respiratory syncytial virus (RSV), a common virus, is able to result in pneumonia and bron...