Measuring changes in transmission of neglected tropical diseases, malaria, and enteric pathogens from quantitative antibody levels.

• Main Authors: Benjamin F Arnold (Author), Mark J van der Laan (Author), Alan E Hubbard (Author), Cathy Steel (Author), Joseph Kubofcik (Author), Katy L Hamlin (Author), Delynn M Moss (Author), Thomas B Nutman (Author), Jeffrey W Priest (Author), Patrick J Lammie (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2017-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:Serological antibody levels are a sensitive marker of pathogen exposure, and advances in multiplex assays have created enormous potential for large-scale, integrated infectious disease surveillance. Most methods to analyze antibody measurements reduce quantitative antibody levels to serop...