Exosomal mitochondrial tRNAs and miRNAs as potential predictors of inflammation in renal proximal tubular epithelial cells

• Main Authors: Glory Ranches (Author), Maximilian Zeidler (Author), Roman Kessler (Author), Martina Hoelzl (Author), Michael W. Hess (Author), Jonathan Vosper (Author), Paul Perco (Author), Herbert Schramek (Author), Kai K. Kummer (Author), Michaela Kress (Author), Anne Krogsdam (Author), Michael Rudnicki (Author), Gert Mayer (Author), Alexander Huettenhofer (Author)
• Format: Book
• Published: Elsevier, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Exosomes have emerged as a valuable repository of novel biomarkers for human diseases such as chronic kidney disease (CKD). From a healthy control group, we performed microRNA (miRNA) profiling of urinary exosomes and compared it with a cell culture model of renal proximal tubular epithelial cells (...