Effects of Toll-like receptor antagonist 4,5-dihydro-3-phenyl-5-isoxasole acetic acid on the progression of kidney disease in mice on a high-fat diet

• Auteurs principaux: Hye Sook Min (Auteur), Jung Eun Kim (Auteur), Mi Hwa Lee (Auteur), Hye Kyoung Song (Auteur), Mi Jin Lee (Auteur), Ji Eun Lee (Auteur), Hyun Wook Kim (Auteur), Jin Joo Cha (Auteur), Young Youl Hyun (Auteur), Jee Young Han (Auteur), Dae Ryong Cha (Auteur), Young Sun Kang (Auteur)
• Format: Livre
• Publié: The Korean Society of Nephrology, 2014-03-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Background: Obesity-related metabolic disorders are closely associated with inflammation induced by innate immunity. Toll-like receptors (TLRs) play a pivotal role in the innate immune system by activating proinflammatory signaling pathways. GIT27 (4,5-dihydro-3-phenyl-5-isoxasole acetic acid) is an...