Developmental Population Pharmacokinetics and Dosing Optimization of Cefepime in Neonates and Young Infants

• Main Authors: Yang Zhao (Author), Bu-Fan Yao (Author), Chen Kou (Author), Hai-Yan Xu (Author), Bo-Hao Tang (Author), Yue-E Wu (Author), Guo-Xiang Hao (Author), Xin-Ping Zhang (Author), Wei Zhao (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

ObjectiveCefepime is used to treat severe infections in neonates. Pharmacokinetic data have only been evaluated among preterm neonates and population pharmacokinetic model lacked external validation. Hence, our aim is to obtain the population pharmacokinetic parameters of cefepime with large samplin...