Consistency in the Assessment of Dried Blood Spot Specimen Size and Quality in U.K. Newborn Screening Laboratories

• Main Authors: Stuart J. Moat (Author), James R. Bonham (Author), Christine Cavanagh (Author), Margaret Birch (Author), Caroline Griffith (Author), Lynette Shakespeare (Author), Clare Le Masurier (Author), Claire Manfredonia (Author), Beverly Hird (Author), Philippa Goddard (Author), Sarah Smith (Author), Laura Wainwright (Author), Rachel S. Carling (Author), Jennifer Cundick (Author), Fiona Jenkinson (Author), Catherine Collingwood (Author), Nick Flynn (Author), Nazia Taj (Author), Mehdi Mirzazadeh (Author), Tejswurree Ramgoolam (Author), Liz Robinson (Author), Amy Headley (Author), Tessa Morgan (Author), David Elliman (Author), Lesley Tetlow (Author)
• Format: Book
• Published: MDPI AG, 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In 2015, U.K. newborn screening (NBS) laboratory guidelines were introduced to standardize dried blood spot (DBS) specimen quality acceptance and specify a minimum acceptable DBS diameter of ≥7 mm. The UK 'acceptable' avoidable repeat rate (AVRR) is ≤2%. To assess inter-laboratory variabil...