Comparison of methods to quantify inducible HIV-1 outgrowth

• Main Authors: P. Nathan Enick (Author), Joseph P. Brooker (Author), Camille M. Tumiotto (Author), Brittany T. Staines (Author), Joseph J. Eron (Author), Deborah K. McMahon (Author), Rajesh T. Gandhi (Author), John W. Mellors (Author), Michele D. Sobolewski (Author)
• Format: Book
• Published: Elsevier, 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The quantitative viral outgrowth assay (qVOA) is the gold standard for measuring inducible, replication-competent HIV-1. Using MOLT4-R5 and SupT1-R5 cell lines instead of allogeneic blasts and HIV-1 RNA detection rather than p24 enzyme-immunoassay (EIA) has been proposed to improve the sensitivity o...