Down-regulation of MSH3 and MSH6 genes in female breast cancer patients receiving taxane-based therapy

• Main Authors: Hanaa R. M. Attia (Author), Dina F. Ayoub (Author), Shereen H. Abd El-Aziz (Author), Mai M. Abdel Wahed (Author), Safa N. Abd El-Fattah (Author), Mahmoud A. Abdel-Monem (Author), Thanaa M. Rabah (Author), Mahmoud M. Kamel (Author), Amany Helal (Author), Mona Hamed Ibrahim (Author)
• Format: Book
• Published: SpringerOpen, 2023-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The DNA in each cell in our body is constantly in danger of becoming damaged. Most DNA damage gets repaired straight away via many different proteins encoded by DNA-repair genes. MSH3 and MSH6 are pivotal DNA repair genes maintaining human genome integrity. Dysregulated expressio...