Electroporation Enhanced Effect of Dystrophin Splice Switching PNA Oligomers in Normal and Dystrophic Muscle

Electroporation Enhanced Effect of Dystrophin Splice Switching PNA Oligomers in Normal and Dystrophic Muscle

Peptide nucleic acid (PNA) is a synthetic DNA mimic that has shown potential for discovery of novel splice switching antisense drugs. However, in vivo cellular delivery has been a limiting factor for development, and only few successful studies have been reported. As a possible modality for improvem...

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Main Authors: Camilla Brolin (Author), Takehiko Shiraishi (Author), Pernille Hojman (Author), Thomas O Krag (Author), Peter E Nielsen (Author), Julie Gehl (Author)
Format: Book
Published: Elsevier, 2015-01-01T00:00:00Z.
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3rd Floor Main Library

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