Myeloid HIF-1 attenuates the progression of renal fibrosis in murine obstructive nephropathy

• প্রধান লেখক: Yu Tateishi (লেখক), Mayuko Osada-Oka (লেখক), Masako Tanaka (লেখক), Masayuki Shiota (লেখক), Yasukatsu Izumi (লেখক), Eiji Ishimura (লেখক), Koka Motoyama (লেখক), Masaaki Inaba (লেখক), Katsuyuki Miura (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Elsevier, 2015-02-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Hypoxia-inducible factors (HIFs) play an important role in the pathogenesis of renal fibrosis. Although the role of macrophage infiltration in the progression of renal fibrosis is well known, the role of macrophage HIF-1 remains to be revealed. To address this question, myeloid specific conditional...