The interaction of classical complement component C1 with parasite and host calreticulin mediates Trypanosoma cruzi infection of human placenta.

• Main Authors: Christian Castillo (Author), Galia Ramírez (Author), Carolina Valck (Author), Lorena Aguilar (Author), Ismael Maldonado (Author), Carlos Rosas (Author), Norbel Galanti (Author), Ulrike Kemmerling (Author), Arturo Ferreira (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND: 9 million people are infected with Trypanosoma cruzi in Latin America, plus more than 300,000 in the United States, Canada, Europe, Australia, and Japan. Approximately 30% of infected individuals develop circulatory or digestive pathology. While in underdeveloped countries transmission i...