Human Ribonuclease 6 Has a Protective Role during Experimental Urinary Tract Infection

• Main Authors: Juan de Dios Ruiz-Rosado (Author), Hanna Cortado (Author), Macie Kercsmar (Author), Birong Li (Author), Gregory Ballash (Author), Israel Cotzomi-Ortega (Author), Yuriko I. Sanchez-Zamora (Author), Sudipti Gupta (Author), Christina Ching (Author), Ester Boix (Author), Ashley R. Jackson (Author), John David Spencer (Author), Brian Becknell (Author)
• Format: Book
• Published: Karger Publishers, 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Mounting evidence suggests that antimicrobial peptides and proteins (AMPs) belonging to the RNase A superfamily have a critical role in defending the bladder and kidney from bacterial infection. RNase 6 has been identified as a potent, leukocyte-derived AMP, but its impact on urinary tract infection...