Homogenization of Amorphous Solid Dispersions Prepared by Electrospinning in Low-Dose Tablet Formulation

• Main Authors: Gergő Fülöp (Author), Attila Balogh (Author), Balazs Farkas (Author), Attila Farkas (Author), Bence Szabó (Author), Balázs Démuth (Author), Enikő Borbás (Author), Zsombor Kristóf Nagy (Author), György Marosi (Author)
• Format: Book
• Published: MDPI AG, 2018-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Low-dose tablet formulations were produced with excellent homogeneity based on drug-loaded electrospun fibers prepared by single-needle as well as scaled-up electrospinning (SNES and HSES). Carvedilol (CAR), a BCS II class compound, served as the model drug while poly (vinylpyrrolidone-co-vinyl acet...