Interleukin-6 from Adipose-Derived Stem Cells Promotes Tissue Repair by the Increase of Cell Proliferation and Hair Follicles in Ischemia/Reperfusion-Treated Skin Flaps

• Main Authors: Chi-Ming Pu (Author), Ya-Chun Chen (Author), Yu-Chen Chen (Author), Tzu-Lin Lee (Author), Yu-Sen Peng (Author), Shun-Hua Chen (Author), Yu-Hsiu Yen (Author), Chung-Liang Chien (Author), Jung-Hsien Hsieh (Author), Yuh-Lien Chen (Author)
• Format: Book
• Published: Hindawi Limited, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The most common postoperative complication after reconstructive surgery is flap necrosis. Adipose-derived stem cells (ADSCs) and their secretomes are reported to mediate skin repair. This study was designed to investigate whether conditioned media from ADSCs (ADSC-CM) protects ischemia/reperfusion-...